Spectrophotometric Determination of Dopamine in Bulk and Dosage Forms Using 2,4-Dinitrophenylhydrazine

Spectrophotometric Determination of drugs in bulk and pharmaceutical dosage forms by using Tetracyanoethylene

ABSTRACT A selective ,sensitive ,accurate UV-Visible spectrophotometric methods have been developed for the estimation of drugs viz.,Diflunisal (DFL),Febuxostat(FBT),Metaxalone(MTX),Fexofenadine methyl ester(FME) and Linezolid(LZD) in bulk and their pharmaceutical dosage forms using Tetracyanoethylene (TCNE) as analytical reagent. These method are based on the formation of charge transfer compl...

Validated Spectrophtometric Method for Determination of Tamsulosin in Bulk and Pharmaceutical Dosage Forms

In this study a sensitive, simple and accurate spectrophotometric method was suggested for determination of tamsulosin in bulk powder and pharmaceutical dosage form based on the formation of an ion-pair complex between the drug and bromocresol green in a buffer solution at pH 3.5. The formed yellow color complex was extracted with chloroform and measured at 415 nm. The optimum reaction conditio...

development of a dye-complex based spectrophotometric method for determination of azithromycin in bulk and dosage forms using alizarin red

Spectrophotometric Methods for the Determination of Sitagliptin and Vildagliptin in Bulk and Dosage Forms

Simple, accurate and precise spectrophotometric methods have been developed for the determination of sitagliptin and vildagliptin in bulk and dosage forms. The proposed methods are based on the charge transfer complexes of sitagliptin phosphate and vildagliptin with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), 7,7,8,8-tetracyanoquinodimethane (TCNQ) and tetrachloro-1,4-benzoquinone (p-chlor...

Spectrophotometric Method for the Determination of Tranexamic Acid in Bulk and Dosage Forms

A simple spectrophotometric method for the determination of tranexamic acid in pure form and pharmaceutical preparations was developed. The method is based on coupling tranexamic acid with 2,6-dichloroquinone-4-chlorimide (DCQ) in dimethyl sulfoxide (DMSO) to produce a colored product which absorbs maximally at wavelength ( ) 670nm. The molar ratio of tranexamic acid: DCQ is 2:1. Beer’s law is ...